Preheat your oven to 350°F (175°C).
Cook the pasta according to the package instructions until al dente, then drain.
In a large bowl, combine the cooked chicken, broccoli, and cooked pasta.
Add the Alfredo sauce, garlic powder, salt, and pepper to the mixture; stir well to combine.
Transfer the mixture into a greased 9x13-inch baking dish and spread it out evenly.
Top the mixture with mozzarella and Parmesan cheese, sprinkling evenly across the dish.
Bake in the preheated oven for 25-30 minutes until the cheese is bubbly and golden brown.
Let the bake sit for 5-10 minutes before serving to allow it to set slightly.